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@@ -764,7 +764,7 @@ <h2 class="sec-title">Scientific work,<br>connected across your stack</h2>
   <h2 class="sec-title">Reference knowledge,<br>one query away</h2>
   <p class="sec-sub">Reference-database plugins give scientists and AI agents read-only access to the genomic, clinical, protein, chemical and ontology resources that analyses depend on, from variant interpretation to target discovery.</p>
   <div class="int-summary">
-    <span class="int-total"><strong>130</strong> reference databases across <strong>9</strong> categories · 100 implemented · 30 scaffolded</span>
+    <span class="int-total"><strong>130</strong> reference databases across <strong>9</strong> categories · 107 implemented · 23 scaffolded</span>
     <a href="https://docs.omnibioai.org/reference-data/database-catalog/" target="_blank" class="int-docs-link">Browse the full catalog in the docs ↗</a>
   </div>
   <div class="int-filters" role="group" aria-label="Filter reference databases by category">
@@ -787,6 +787,7 @@ <h2 class="sec-title">Reference knowledge,<br>one query away</h2>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">ClinGen</span><span class="int-desc">Gene–disease validity and dosage sensitivity</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">ClinVar</span><span class="int-desc">Clinical significance of human variants</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">COSMIC</span><span class="int-desc">Cancer Gene Census via licensed downloads</span></a>
+      <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">CPIC</span><span class="int-desc">Pharmacogenomic guidelines and dosing recommendations</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">dbNSFP</span><span class="int-desc">Functional predictions for missense variants</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">dbSNP</span><span class="int-desc">rsIDs, alleles and genomic placements</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">dbVar</span><span class="int-desc">NCBI structural-variation studies and variants</span></a>
@@ -794,12 +795,14 @@ <h2 class="sec-title">Reference knowledge,<br>one query away</h2>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">DGV</span><span class="int-desc">Structural variants from validated local snapshots</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">Ensembl</span><span class="int-desc">Genes, transcripts, sequences, variants and homology</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">Gene2Phenotype</span><span class="int-desc">Curated gene–disease panels from EMBL-EBI</span></a>
+      <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">GeneReviews</span><span class="int-desc">Expert disease reviews by gene and OMIM</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">Genomics England PanelApp</span><span class="int-desc">Expert-reviewed diagnostic gene panels</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">gnomAD</span><span class="int-desc">Population allele frequencies and gene constraint</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">GWAS Catalog</span><span class="int-desc">Studies, traits and reported associations</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">HGMD</span><span class="int-desc">Licensed clinical variants via a local or gateway provider</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">HGNC</span><span class="int-desc">Approved human gene symbols and names</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">MARRVEL</span><span class="int-desc">Rare-variant evidence across model organisms</span></a>
+      <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">MaveDB</span><span class="int-desc">Multiplexed assays of variant effect scores</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">MedGen</span><span class="int-desc">Medical-genetics concepts, genes and features</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">NCBI Entrez</span><span class="int-desc">Gene, protein, nucleotide and taxonomy search</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">OMIM</span><span class="int-desc">Mendelian genes, disorders and inheritance</span></a>
@@ -809,13 +812,10 @@ <h2 class="sec-title">Reference knowledge,<br>one query away</h2>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">SNPedia</span><span class="int-desc">Community variant and genotype annotations</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">UCSC Genome Browser</span><span class="int-desc">Genome databases, tracks and region data</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">Clinvitae <span class="int-tag">scaffold</span></span><span class="int-desc">Aggregated clinical variant reports</span></a>
-      <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">CPIC <span class="int-tag">scaffold</span></span><span class="int-desc">Pharmacogenomic prescribing guidelines</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">GeneCards <span class="int-tag">scaffold</span></span><span class="int-desc">Integrated human gene summaries</span></a>
-      <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">GeneReviews <span class="int-tag">scaffold</span></span><span class="int-desc">Expert-authored disease reviews</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">GWAS Summary Statistics <span class="int-tag">scaffold</span></span><span class="int-desc">Full summary statistics for GWAS</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">LOVD <span class="int-tag">scaffold</span></span><span class="int-desc">Locus-specific variant databases</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">Mastermind <span class="int-tag">scaffold</span></span><span class="int-desc">Variant evidence from the literature</span></a>
-      <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">MaveDB <span class="int-tag">scaffold</span></span><span class="int-desc">Multiplexed assays of variant effect</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">NCBI Gene <span class="int-tag">scaffold</span></span><span class="int-desc">Gene records and annotation</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">OncoKB <span class="int-tag">scaffold</span></span><span class="int-desc">Precision-oncology variant knowledge</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#genes-variants--clinical-genetics-40" target="_blank"><span class="int-name">RefSeq <span class="int-tag">scaffold</span></span><span class="int-desc">NCBI reference sequences</span></a>
@@ -839,12 +839,12 @@ <h2 class="sec-title">Reference knowledge,<br>one query away</h2>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">NCBI GEO</span><span class="int-desc">Expression series, datasets, platforms and samples</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">NCBI SRA</span><span class="int-desc">Sequence Read Archive studies, runs and samples</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">PanglaoDB</span><span class="int-desc">Single-cell cell-type marker genes</span></a>
+      <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">TCGA</span><span class="int-desc">Open-access TCGA cases, files and mutations via GDC</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">All of Us <span class="int-tag">scaffold</span></span><span class="int-desc">Controlled-access research cohort</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">CCLE <span class="int-tag">scaffold</span></span><span class="int-desc">Cancer cell-line omics profiles</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">dbGaP <span class="int-tag">scaffold</span></span><span class="int-desc">Controlled-access genotype–phenotype studies</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">DepMap <span class="int-tag">scaffold</span></span><span class="int-desc">Cancer dependency and CRISPR screens</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">EGA <span class="int-tag">scaffold</span></span><span class="int-desc">Controlled-access genome–phenome archive</span></a>
-      <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">TCGA <span class="int-tag">scaffold</span></span><span class="int-desc">The Cancer Genome Atlas cohorts</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#expression-omics--cohorts-19" target="_blank"><span class="int-name">UK Biobank <span class="int-tag">scaffold</span></span><span class="int-desc">Controlled-access population cohort</span></a>
     </div>
   </div>
@@ -874,24 +874,24 @@ <h2 class="sec-title">Reference knowledge,<br>one query away</h2>
   <div class="int-group" data-group="drugs-chemistry">
     <div class="int-group-head"><h3 class="int-group-title">Drugs, Chemistry &amp; Metabolomics</h3><span class="int-group-count">20</span><p class="int-group-sub">Drugs and targets, chemical compounds, enzymes, lipids, metabolomics and toxicogenomics.</p></div>
     <div class="int-grid">
+      <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">BindingDB</span><span class="int-desc">Measured protein–ligand binding affinities</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">BRENDA</span><span class="int-desc">Enzyme kinetics, reactions and inhibitors</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">ChEBI</span><span class="int-desc">Curated small molecules, structures and roles</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">CTD</span><span class="int-desc">Chemical–gene–disease relationships, indexed locally</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">DGIdb</span><span class="int-desc">Drug–gene interactions and druggable genes</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">DrugBank</span><span class="int-desc">Licensed drug, product and interaction lookup</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">DrugCentral</span><span class="int-desc">Approved drugs, targets and indications</span></a>
+      <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">Drugs@FDA</span><span class="int-desc">FDA drug applications, products and submissions</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">Guide to PHARMACOLOGY</span><span class="int-desc">Drug targets and their ligands</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">HMDB</span><span class="int-desc">Availability status only; access is gated</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">LIPID MAPS</span><span class="int-desc">Lipid structures and classification</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">MassBank</span><span class="int-desc">Mass-spectrometry reference spectra</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">MetaboLights</span><span class="int-desc">Metabolomics studies, assays and protocols</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">OpenFDA</span><span class="int-desc">Adverse events, labels, recalls and NDC</span></a>
+      <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">Pharos</span><span class="int-desc">Drug targets by development level, ligands and diseases</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">PubChem</span><span class="int-desc">Compounds, substances and bioassays</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">RxNorm</span><span class="int-desc">Normalized drug names, NDCs and drug classes</span></a>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">SwissLipids</span><span class="int-desc">Curated lipid structures and metabolism</span></a>
-      <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">BindingDB <span class="int-tag">scaffold</span></span><span class="int-desc">Measured protein–ligand binding affinities</span></a>
-      <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">Drugs@FDA <span class="int-tag">scaffold</span></span><span class="int-desc">FDA-approved drug products and applications</span></a>
-      <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">Pharos <span class="int-tag">scaffold</span></span><span class="int-desc">Illuminating the Druggable Genome targets</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">SIDER <span class="int-tag">scaffold</span></span><span class="int-desc">Marketed drug side effects</span></a>
       <a class="int-card int-card-scaffold" href="https://docs.omnibioai.org/reference-data/database-catalog/#drugs-chemistry--metabolomics-20" target="_blank"><span class="int-name">T3DB <span class="int-tag">scaffold</span></span><span class="int-desc">Toxins and their targets</span></a>
     </div>
@@ -954,7 +954,7 @@ <h2 class="sec-title">Reference knowledge,<br>one query away</h2>
       <a class="int-card" href="https://docs.omnibioai.org/reference-data/database-catalog/#other--cross-domain-2" target="_blank"><span class="int-name">NVIDIA BioNeMo</span><span class="int-desc">Open biomolecular models and recipes</span></a>
     </div>
   </div>
-  <p class="int-note">Entries tagged <span class="int-tag">scaffold</span> are registered but not yet connected to their upstream resource; the other 100 call it in source. A few connectors report availability status only, where the upstream offers no usable API. Licensed resources (for example COSMIC, DrugBank, HGMD) need your own licence and credentials. Counts are from the docs catalog generated 2026-09-19, updated for connectors implemented since; no entry is asserted as deployed or operationally verified.</p>
+  <p class="int-note">Entries tagged <span class="int-tag">scaffold</span> are registered but not yet connected to their upstream resource; the other 107 call it in source. A few connectors report availability status only, where the upstream offers no usable API. Licensed resources (for example COSMIC, DrugBank, HGMD) need your own licence and credentials. Counts are from the docs catalog generated 2026-09-19, updated for connectors implemented since; no entry is asserted as deployed or operationally verified.</p>
 </section>
 
 <hr class="divider">
@@ -972,7 +972,7 @@ <h2 class="cat-title">What's in the platform</h2>
     <a class="cat-tile" href="https://docs.omnibioai.org/workflows-catalog/" target="_blank"><span class="cat-num">1000+</span><span class="cat-label">Workflows</span><span class="cat-detail">869 in the docs catalog, across 102 domains<span class="cat-bar" role="img" aria-label="Engine mix in the docs catalog: Nextflow 861 · WDL 5 · Snakemake 2 · CWL 1"><span class="cat-bar-seg cat-seg-0" style="flex:861" title="Nextflow: 861"></span><span class="cat-bar-seg cat-seg-1" style="flex:5" title="WDL: 5"></span><span class="cat-bar-seg cat-seg-2" style="flex:2" title="Snakemake: 2"></span><span class="cat-bar-seg cat-seg-3" style="flex:1" title="CWL: 1"></span></span><span class="cat-legend">Engine mix in docs catalog: Nextflow 861 · WDL 5 · Snakemake 2 · CWL 1</span></span></a>
     <a class="cat-tile" href="https://docs.omnibioai.org/plugins/" target="_blank"><span class="cat-num">501</span><span class="cat-label">Workbench plugins</span><span class="cat-detail">Across 22 categories, including 66 integrations</span></a>
     <a class="cat-tile" href="https://docs.omnibioai.org/tools/" target="_blank"><span class="cat-num">12,276</span><span class="cat-label">TES tool definitions</span><span class="cat-detail">8 execution backends · 9,061 auto-imported and not yet verified</span></a>
-    <a class="cat-tile" href="https://docs.omnibioai.org/reference-data/database-catalog/" target="_blank"><span class="cat-num">130</span><span class="cat-label">Reference database plugins</span><span class="cat-detail">100 implemented · 30 scaffolded</span></a>
+    <a class="cat-tile" href="https://docs.omnibioai.org/reference-data/database-catalog/" target="_blank"><span class="cat-num">130</span><span class="cat-label">Reference database plugins</span><span class="cat-detail">107 implemented · 23 scaffolded</span></a>
     <a class="cat-tile" href="https://docs.omnibioai.org/api-reference/" target="_blank"><span class="cat-num">219</span><span class="cat-label">API routes</span><span class="cat-detail">Found in source across 8 services · 109 documented publicly</span></a>
   </div>
   <p class="cat-note">Plugin, tool, reference database and API counts are read from the documentation's generated catalogs (19 Sep 2026). They describe what is registered or configured in source, not that every entry has been tested or deployed. <a href="https://docs.omnibioai.org/quality-and-trust/" target="_blank">How to read these figures ↗</a></p>