diff --git a/src-python/amazon/ion/equivalence.py b/src-python/amazon/ion/equivalence.py
index 01358c3e..d24458eb 100644
--- a/src-python/amazon/ion/equivalence.py
+++ b/src-python/amazon/ion/equivalence.py
@@ -169,7 +169,7 @@ def _timestamps_eq(a, b):
             if isinstance(b, Timestamp):
                 # Both operands declare their precisions. They are only equivalent if their precisions are the same.
                 if a.precision is b.precision and a.fractional_precision is b.fractional_precision \
-                        and a.fractional_seconds == b.fractional_seconds:
+                        and _decimals_eq(a.fractional_seconds, b.fractional_seconds):
                     break
                 return False
             elif a.precision is not TimestampPrecision.SECOND or a.fractional_precision != MICROSECOND_PRECISION:
diff --git a/tests/test_equivalence.py b/tests/test_equivalence.py
index 6cb7001e..9e54cb91 100644
--- a/tests/test_equivalence.py
+++ b/tests/test_equivalence.py
@@ -193,6 +193,11 @@ def _ion_nature(_ion_nature_cls, ion_type, value=None, annotations=()):
         _ts(1999, 12, 31, 23, 59, off_hours=0, off_minutes=-1, precision=_TP.SECOND),
         None,
     ),
+    (
+        # Timestamps with different fractional precisions beyond microseconds are not equivalent.
+        _timestamp(_ts(2000, precision=_TP.SECOND, fractional_seconds=Decimal('0.000000'))),
+        _timestamp(_ts(2000, precision=_TP.SECOND, fractional_seconds=Decimal('0.0000000'))),
+    ),
     (
         # Timestamps with different fractional seconds are not equivalent.
         _timestamp(_ts(2000, 1, 1, 1, precision=_TP.SECOND, fractional_seconds=Decimal('0.123456789'))),