Hello
I am curious if chromVAR would allow the use of paired designs, in the function differentialDeviations.
Our dataset compares two cell types isolated from 6 patients. When we perform differential DNA accessibility testing, we see a big improvement (in number of DARs identified) when we use a paired (by patient) design. I was wondering if chromVAR would offer this level of flexibility.
Thanks
Alex
Hello
I am curious if chromVAR would allow the use of paired designs, in the function
differentialDeviations.Our dataset compares two cell types isolated from 6 patients. When we perform differential DNA accessibility testing, we see a big improvement (in number of DARs identified) when we use a paired (by patient) design. I was wondering if chromVAR would offer this level of flexibility.
Thanks
Alex