Biostatistician and Researcher focusing on: Early Phase Oncology Dose Optimization, Rare Diseases, Time to Event Data, Longitudinal Data, Bayesian Variable Selection, Multivariate Joint Modeling
This project evaluates radiopharmaceutical dose administration in nuclear medicine procedures by comparing typical administered doses with national Diagnostic Reference Levels (DRL). The study aims to assess dose optimization practices and ensure radiation safety compliance.
🧬 Model and optimize CAR-T therapy for glioblastoma using advanced spatial fractional reaction-diffusion techniques and tumor microenvironment insights.
LOGOS (Longitudinal Optimization of Global Outcomes and Strategies) — Bridging mathematical treatment theory and clinical evidence through PK/PD modeling and patient-level prediction.
LOGOS (Longitudinal Optimization of Global Outcomes and Strategies) — Mathematical optimization of finite-course PK/PD regimens using clinical pharmacological data and constrained optimal control.
R code for simulation, calibration, and exact strong-FWER verification of active-count-coupled multi-arm efficacy-toxicity monitoring.
Deterministic, mechanistic, auditable model-informed precision dosing (MIPD): PK/PD engine, Bayesian TDM, Monte Carlo PTA, curated cited drug library. Zero runtime dependencies.
LOGOS (Longitudinal Optimization of Global Outcomes and Strategies) — Constrained mathematical optimization of finite-course PK/PD regimens using individual pharmacological models.
LOGOS (Longitudinal Optimization of Global Outcomes and Strategies): A mathematical framework for PK/PD treatment cycling, recovery dynamics, and clinical restart decisions.
Smart CT Dose Optimizer - Professional radiation dose management tool
Spatial fractional reaction-diffusion model optimizing CAR-T immunotherapy for glioblastoma with tumor microenvironment integration
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