flywire

A curated list of fruit fly connectome projects: MaleCNS, FlyWire, brain simulations, embodied models, games, and research tools.

Python library for analysis of neuroanatomical data.

Explore the FlyWire Connectome

Embodied Drosophila: 138,639-neuron whole-brain connectome simulation (FlyWire v783) in a biomechanical body (NeuroMechFly v2 / MuJoCo). Vision, olfaction, gustation, flight, and emergent behaviors — all from the real connectome.

Tools to work with the FlyWire connectome. Fully interoperable with navis.

🪰 Chat with 138,000 neurons — whole-brain fruit fly simulation with natural language interface and dopamine learning

Windows port (C#/.NET 8/Direct3D11) of desktop-vibe-fly - a 3D fruit fly on your desktop driven by a live FlyWire connectome simulation, with a vibecode nose for AI agent activity. Fork/port of kulikov0/desktop-vibe-fly, itself a fork of DenisSergeevitch/desktop-fly.

A living fruit fly in your browser. Feed it and its real feeding circuit fires — 448 neurons from the Drosophila connectome, simulated live.

Virtual organisms powered by real brain wiring. Connectome data → spiking neural network → physics body → emergent behavior.

Linux/X11 port of DesktopFly (desktop-fly): a 3D fruit fly on your GNOME desktop, driven by a live spiking simulation of the real FlyWire connectome. Python + GTK3 + cairo, no Electron.

Poke a neuron in the fruit fly brain and watch what fires: a laptop-speed LIF simulation of the full FlyWire connectome

A bio-inspired RNN that fuses Drosophila connectome constraints with valence-modulated plasticity. Uses reservoir computing: fixed realistic circuits for innate odor paths plus learnable dopamine-gated synapses. Captures learning dynamics and aversive-conditioning limits from hardwired biases.

Écrase la mouche : la mouche s'échappe grâce à son vrai circuit de fuite (connectome FlyWire, 26 580 neurones simulés dans le navigateur)

Whole-brain Drosophila simulation at 2.2x real time on 4 CPU cores, no GPU. 138,639 neurons bit-identical to the reference, with nine switchable neuron models and a live 3D interface.

Training the FlyWire Drosophila connectome to play chess. Leads with why 3600 Elo is 151x out of reach, then plans the strongest achievable version. Includes a playable 3D board and a live neuropil activity panel.

Keep a fruit fly alive for fifty days and teach her tricks. Her reactions run on the real FlyWire connectome — 138,639 neurons in your browser.

It is the codes

Stimulate a real fruit fly's brain in your browser. Leaky integrate-and-fire over the FlyWire connectome — 138,639 neurons, 2.7M connections, 60 fps, no dependencies.

Whole-brain Drosophila connectome simulation (FlyWire v783, 138 639 neurons) that decides on-chain buybacks of $FLY on Robinhood Chain by proboscis extension. The proof behind inthebrainofafly.com