Software UART for AVR microcontrollers
A large scale off-target analysis tool for CRISPR/Cas9 genome editing system
Commands, scripts, and data for reanalysis of "Unexpected mutations after CRISPR–Cas9 editing in vivo"
Source-aware benchmark and validation-priority resource for high-mismatch genome-editing off-target prioritization.
Research safety-triage workflow for CRISPR base editing in sickle cell disease and beta-thalassemia; covers bystanders, off-targets, HBG1/HBG2 risks, and evidence.
MMIO stub library for off-target embedded unit tests
Automated 16-step siRNA design pipeline as a portable Agent Skill: siDirect design, thermodynamics, miRNA seed, off-target BLAST, gnomAD variants, multi-species off-target, 21-parameter scoring, benchmarking against approved drugs. 自动化 siRNA 设计流水线。
Re-analysis of a Boltz-2 vs SEA off-target benchmark: both structural confidence metrics discriminate at chance, the affinity head does not.
Commensal-sparing CRISPR guide design — target one bacterium, spare the microbiome. Narrow-spectrum, strain-selective, in-browser, free.
Local CRISPR-Cas9 guide off-target scanner. Core PAM scan verified correct via property testing against 500 random sequences; added a bound on max_mismatches to prevent degenerate output near the random-match noise floor.
UART module for AVR microcontrollers
CE-specific qPCR primer design pipeline: Primer3 + pair-wise BLAST against genome & curated RefSeq mRNA to select junction-spanning assays.
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