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Spatial Transcriptomics bridges the gap between cellular identity and spatial geography. ST preserves this architecture, allowing scientists to see exactly where genes are expressed and how cells interact within their native neighborhoods.
Spatial transcriptomics investigation of immune-program colocalization, multicellular niches, and tissue organization in breast cancer using 10x Visium.
Codes associated to the analyses performed in Dauyey Velds et al., "A spatial single-cell transcriptomic atlas of metastatic breast cancer progression".
R scripts for preprocessing, pathway scoring, Bayesian modeling, and Cox proportional hazards analyses applied to the SCAPeSCLC dataset, integrating GeoMx Cancer Transcriptome Atlas expression and survival outcomes in ES-SCLC patients treated with chemo-immunotherapy.