Sex-stratified computational pipeline for ALS drug target discovery integrating iPSC transcriptomic reversal, ChEMBL pharmacological annotation, and multi-model machine learning prioritisation.
machine-learning string random-forest xgboost logistic-regression als transcriptomics chembl pu-learning target-discovery chembl-web-client target-prioritisation phenotypic-rescue transcriptomic-reversal sex-stratified
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Updated
Aug 20, 2026 - Jupyter Notebook