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hemoglobin

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A reproducible bioinformatics case study of the hemoglobin beta E6V mutation, connecting FASTA parsing, pairwise alignment, BLOSUM scoring, BLAST evidence, and PDB-based structural contacts to explain how one amino-acid change becomes biologically meaningful. It contains scripts, figures, reports, and clear limits on what the analysis can clai

  • Updated Mar 14, 2026
  • Python

Reproducible NHANES codebase auditing whether CBC-based anemia classifiers retain hemoglobin-related target information after HGB removal through analyzer-equation reconstruction, controlled feature-ladder experiments, classifier comparisons, survey-aware inference, and out-of-cycle replication.

  • Updated Sep 8, 2026
  • Python

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